Research Articles
From Resistance to Resilience: Mastering the CRM Model for Robust Cancer Drug Discovery
This article provides a comprehensive guide to the Cell Repopulation Model (CRM) of community resilience in oncology research.
CRISPRi for Orthogonal Genetic Circuit Design: Principles, Protocols, and Precision Engineering in Synthetic Biology
This article provides a comprehensive guide for researchers and drug development professionals on using CRISPR interference (CRISPRi) for orthogonal genetic circuit design.
CRISPR Engineering of Microbial Consortia: A Next-Generation Platform for Synthetic Biology and Therapeutic Development
This article provides a comprehensive guide for researchers and biotechnology professionals on applying CRISPR-based genome editing to engineer microbial consortia.
Streamlining Cellular Factories: Advanced CRISPR Strategies for Targeted Gene Deletion to Minimize Metabolic Burden
This article provides a comprehensive guide for researchers and bioprocess engineers on using CRISPR-Cas systems for targeted gene deletion to alleviate metabolic burden in engineered microbial hosts.
COMMIT Gap-Filling: A Comprehensive Guide for Building Accurate Community Metabolic Models in Biomedical Research
This article provides a detailed exploration of the COMMIT (Community Model Integration and Testing) methodology for gap-filling in genome-scale metabolic models (GEMs) of microbial communities.
Unlocking Nature's Blue Carbon Hack: C4 Photosynthesis in Marine Macroalgae and Its Biomedical Implications
This article provides a comprehensive review of C4 photosynthesis in marine macroalgae, a significant yet underexplored adaptation to carbon limitation in aquatic environments.
Beyond Photosynthesis: C4 Acid-Dependent O2 Evolution as a Novel Bioenergetic Assay for Drug Discovery and Metabolic Research
This article provides a comprehensive guide to the C4 acid-dependent O2 evolution experiment, a critical assay for probing the photorespiratory and metabolic functions of plant and algal systems.
Bray-Curtis Dissimilarity in Anammox Communities: A Guide for Microbial Ecologists and Environmental Researchers
This article provides a comprehensive guide to Bray-Curtis dissimilarity analysis for anammox (anaerobic ammonium oxidation) microbial communities.
Hierarchical Data Checking: Ensuring Quality in Citizen Science and Volunteer-Collected Biomedical Research Data
This article explores the critical role of hierarchical data checking frameworks in managing volunteer-collected data for biomedical research.
ACE Richness vs Shannon Diversity: Which Metric Best Reveals Anammox Community Dynamics for Bioreactor Optimization?
This article provides a comprehensive guide for microbial ecologists and environmental biotechnologists on interpreting ACE richness and Shannon diversity indices for anammox communities.